Rosacea in Crohn's Disease: Effect of Rifaximin.

Leonard B. Weinstock, MD Washington University School of Medicine, St Louis, MO; Specialists in Gastroenterology, LLC, St Louis, MO Rosacea is a skin disease that manifests as flushing, persistent skin redness (ie, erythematous form), small rounded bumps on the skin (ie, papulopustular form), or dilated superficial blood vessels (ie, telangiectasia). The pathophysiology of rosacea is unknown, but alterations in the immune system, either by organic disease (eg, inflammatory bowel disease [IBD]) or immune-altering medications, may predispose individuals to the development of rosacea. Standard therapy for rosacea includes topical therapies (eg, sodium sulfacetamide) and oral antibiotic medications (eg, doxycycline, tetracycline, minocycline, erythromycin, and metronidazole) for patients who are intolerant of topical therapies.